Two strikes against CLL
نویسندگان
چکیده
منابع مشابه
Two strikes lead to leukemia
New genetic mapping studies explain why a certain mouse strain is predisposed to developing fatal leukemia. Turcotte et al., reporting on page 881, identify a point mutation in the transcription factor IRF-8 (interferon regulatory factor 8) that abolishes its function and sets the stage for a second, leukemia-triggering mutation. The recombinant mouse strain BXH-2 is known to develop first a my...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2016-06-719864